Iranian and US negotiators resumed talks in Rome on Friday to resolve a decades-long dispute over Iran's nuclear ambitions, according to reports by Iranian media.

Iranian Foreign Minister Abbas Araqchi and Trump's Middle East envoy Steve Witkoff are to lead the fifth round of talks.

US President Donald Trump wants to decrease Tehran's potential to produce a nuclear weapon that could trigger a regional nuclear arms race.

Meanwhile, Iran wants to be rid of devastating sanctions on its oil-based economy.